Atropine Eye Drops



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Atropine eye drops are types of drops that are used to dilute or enlarge the pupil of the eye. This action is called mydriasis.

It is used also to inhibit accommodation and make the patient unable to focus for near tasks. This action is called cycloplegia.

It consists mainly of atropine sulphate with benzalkonium chloride as a preservative.

It comes in both eye drops and eye ointment.

The action of this eye drop can last from 1 to 2 weeks.

Storage instructions:

It should be stored between 15- 25°C ( 59-86°F)and keep it tightly closed.

you should always KEEP it and any other medications away from the children and pets.

How it dilutes pupil?

There are two muscles in the pupil, one is called sphincter papillae that is responsible for constriction of the pupil and the other is called dilutor pupillae which will dilute the pupil.

Sphincter pupillae is innervated by a special nervous system called parasympethatic nervous system. This system will innervate sphincter papillae through a special receptor called muscarinic receptor.

Atropine which is called anti-muscarinic drug will act to inhibit this these receptors from receiving innervation from parasympathetic system, so the sphincter will not constrict, making the pupil to dilute because there is no opposing action to dilutor pupillae

How it will inhibit accommodation ?

In the same mechanism, it will also act on ciliary muscle which is responsible for accommodation.

Pregnancy and Breastfeeding

The safety of atropine during pregnancy and breastfeeding has not been established. You should seek medical advice about this issue from your doctor.




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